作者：杨培增
页数：888
出版社：人民卫生出版社
出版日期：2021
ISBN：9787117312943
电子书格式：pdf/epub/txt
内容简介
本书总结了作者近三十年来在临床实践中得出的经验和正确的思维模式，收录了3000多张图片，这些图片不仅展现了典型眼部病变，也为全世界眼科医生描绘了一套完整的葡萄膜炎谱系。全书囊括了各种葡萄膜炎类型，尤其是在中国患者中常见的类型，可以帮助医生根据临床检查和患者病史作出快速和正确诊断。本书还涉及世界范围内关于葡萄膜炎诊断和治疗的近期新进展和研究成果，对各级眼科医生、风湿病专家以及其他相关领域医生的临床实践和科研工作都有很大帮助。
作者简介
杨培增，男，1957年6月出生于河南省濮阳县。教授、博士研究生导师。教育部长江学者特聘教授、国家杰出青年基金获得者、国务院政府特殊津贴获得者，国务院学位委员会第五、六届学科评议组成员，重庆市两江学者特聘教授、重庆市首届首席医学专家、十八大党代表、国际眼炎症学会执行理事、亚太眼内炎症学会执行理事、国际Behcet病学会理事、国际葡萄膜炎研究组成员，The Lancet、Nature Genetic、JACI、Ann Rheum Dis等50余份SCI收录杂志审稿专家，中华医学会眼科学分会副主任委员、眼科学重庆市市级重点实验室主任、重庆市眼科研究所所长、重庆医科大学附属第一医院眼科主任。
从事临床、科研、教学工作40年，以项目负责人获国家自然科学基金创新群体基金、国家自然科学基金重大国际合作研究项目(3项)、国家自然科学基金重点项目(2项)、国家重点研发计划、科技部“十一五”支撑计划等，在Nature Genetics及其他SCI收录杂志发表第一作者和(或)通讯作者的论文200多篇，独立完成著作460万字，主编五年制规划教材及其他专著5部，以第一完成人获国家科技进步奖二等奖(2项)、三等奖(1项)，省部级科技进步一等奖6项，亚太眼内炎症学会杰出成就奖、亚太眼科学会成就奖、重庆市科技突出贡献奖、重庆市富民兴渝贡献奖、中华眼科杰出成就奖、中美眼科学会金钥匙奖、中美眼科学会金苹果奖和第六届中国医师奖，被授予卫生部有突出贡献中青年专家、全国杰出专业技术人才、全国“五一劳动奖章”、全国模范教师和全国优秀科技工作者等称号。
目录
Part I Overview
1 Anatomy and Physiology of Uveitis
1.1 Anatomy of the Eyeball
1.2 Eye Content
1.3 The Cornea
1.4 The Sclera
1.5 The Uveal Tract
1.6 The Retina
1.7 The Aqueous Humor
1.8 The Lens
1.9 The Vitreous
References
2 Classification of Uveitis
2.1 Classification of Uveitis
2.2 Anatomic Classification
2.3 Classification Based on Course
2.4 Classification Based on Clinical and Pathological Features
2.5 Classification Based on Causative Agents
References
Part II Diagnosis of Uveitis
3 History-Taking in Uveitis Patients
3.1 Overview
3.2 Geographical and Racial Distribution of Uveitis
3.3 Age at Onset of Uveitis
3.4 Sex Distribution in Uveitis
3.5 Unilateral or Bilateral Involvement
3.6 Family History
3.7 Personal History
3.8 Systemic Manifestations (Systemic Disorders)
References
4 Ocular Examinations
4.1 The Purposes of Ocular Examinations in Uveitis Patients
4.2 Visual Acuity
4.3 Lid Changes May Be Associated with the Following Entities of Uveitis
4.4 Conjunctival Changes May Be Seen in the Following Uveitis Entities
4.5 Episcleritis
4.6 Scleritis
4.7 Red Reflex Through the Sclera
4.8 Corneal Changes
4.9 Ciliary Injection
4.10 Keratic Precipitates (KPs)
4.11 Anterior Chamber Alterations
4.12 Changes in the Iris and Pupil
4.13 Changes of the Anterior Chamber Angle
4.14 Changes of the Lens
4.15 Changes of the Vitreous
4.16 The Fundus Changes in Uveitis
References
5 Auxiliary Ocular Examinations
5.1 Ultrasound Biomicroscopy (UBM)
5.1.1 Overview
5.1.2 The Changes Disclosed by UBM in Uveitis Patients
5.2 Ultrasonography
5.2.1 Overview
5.2.2 The Changes Detected by Ultrasonography in Uveitis Patients
5.3 Fundus Fluorescein Angiography (FFA)
5.3.1 Overview
5.3.2 The Changes Detected by FFA in Uveitis Patients
5.4 Indocyanine Green Angiography (ICGA)
5.4.1 Overview
5.4.2 The Changes Detected by ICGA in Uveitis Patients
5.5 Optical Coherence Tomography (OCT) Imaging
5.5.1 Overview
5.5.2 The Changes Disclosed by OCT in Uveitis Patients
References
6 Systemic Imaging and Laboratory Investigations
6.1 X-ray
6.2 Computed Tomography (CT)
6.3 Magnetic Resonance Imaging (MRI)
6.4 Laboratory Investigations
References
Part III Treatment of Uveitis
7 Ideology, Fundamental Principles, and Strategies in Management of Uveitis
7.1 Ideology in Uveitis Management
7.2 Fundamental Principles
7.3 Strategies
References
8 Corticosteroids
8.1 Overview
8.2 Topical Corticosteroids
8.3 Periocular Corticosteroids
8.4 Intravitreal Corticosteroids
8.5 Systemic Corticosteroids
References
9 Steroid-sparing Immunosuppressive Agents
9.1 Overview
9.2 Cyclophosphamide
9.3 Chlorambucil
9.4 Cyclosporine A (CsA)
9.5 FK506
9.6 Methotrexate
9.7 Azathioprine
9.8 Mycophenolate Mofetil
9.9 Biological Agents
References
10 Non-steroidal Anti-inflammatory Drugs
10.1 Overview
10.2 Topical NSAIDs
10.3 Systemic NSAIDs
References
11 Complications and Their Management
11.1 Overview
11.2 Cataract
11.3 Ocular Hypertension and Glaucoma
11.4 Macular Edema
References
Part IV Specific Uveitis Entities, Scleritis and Episcleritis
12 Acute Anterior Uveitis
12.1 Definition
12.2 Epidemiology
12.3 Common Entities
12.4 Less Common Entities
12.5 Symptoms
12.6 Signs
12.7 Complications
12.8 Diagnosis
12.9 Differential Diagnosis
12.10 Treatment
12.11 Prognosis
References
13 Intermediate Uveitis
13.1 Definition
13.2 Epidemiology
13.3 Etiology and Pathogenesis
13.4 Clinical Manifestations
13.4.1 Symptoms
13.4.2 Signs
13.5 Complications
13.6 Diagnosis
13.7 Differential Diagnosis
13.8 Treatment
13.9 Prognosis
References
14 Posterior Uveitis
14.1 Definition
14.2 Epidemiology
14.3 Etiology and Pathogenesis
14.4 Entities of Posterior Uveitis
14.5 Diagnosis and Differential Diagnosis
14.6 Treatment
14.7 Prognosis
References
15 Uveitis Associated with Ankylosing Spondylitis
15.1 Definition
15.2 Epidemiology
15.3 Etiology and Pathogenesis
15.4 Systemic Manifestations
15.5 Ocular Manifestations
15.6 Complications
15.7 Diagnosis
15.8 Differential Diagnosis
15.9 Treatment
15.10 Prognosis
References
16 Uveitis Associated with Reactive Arthritis
16.1 Definition
16.2 Epidemiology
16.3 Systemic Manifestations
16.4 Ocular Manifestations
16.5 Diagnosis
16.6 Differential Diagnosis
16.7 Treatment
16.8 Prognosis
References
17 Uveitis Associated with Psoriasis
17.1 Definition
17.2 Epidemiology
17.3 Etiology and Pathogenesis
17.4 Systemic Manifestations
17.5 Ocular Manifestations
17.6 Complications
17.7 Diagnosis
17.8 Differential Diagnosis
17.9 Treatment
17.10 Prognosis
References
18 Uveitis Associated with Inflammatory Bowel Diseases
18.1 Definition
18.2 Epidemiology
18.3 Etiology and Pathogenesis
18.4 Systemic Manifestations
18.5 Ocular Manifestations
18.6 Complications
18.7 Diagnosis
18.8 Differential Diagnosis
18.9 Treatment
18.10 Prognosis
References
19 Anterior Uveitis Associated with Herpesviruses
19.1 Definition
19.2 Epidemiology
19.3 Etiology and Pathogenesis
19.4 Clinical Manifestations
19.5 Complications
19.6 Diagnosis
19.7 Differential Diagnosis
19.8 Treatment
19.9 Prognosis
References
20 Fuchs Syndrome
20.1 Definition
20.2 Epidemiology
20.3 Etiology and Pathogenesis
20.4 Clinical Manifestations
20.5 Complications
20.6 Diagnosis
20.7 Differential Diagnosis
20.8 Treatment
20.9 Prognosis
References
21 Posner-Schlossman Syndrome
21.1 Definition
21.2 Epidemiology
21.3 Etiology and Pathogenesis
21.4 Clinical Manifestations
21.5 Complications
21.6 Diagnosis
21.7 Differential Diagnosis
21.8 Treatment
21.9 Prognosis
References
22 Uveitis in Children
22.1 Definition
22.2 Epidemiology
22.3 Specific Concerns About Uveitis in Children
22.4 Complications
22.5 Diagnosis
22.6 Treatment
22.7 Prognosis
References
23 Uveitis-associated with Juvenile Idiopathic Arthritis
……
1 Anatomy and Physiology of Uveitis
1.1 Anatomy of the Eyeball
1.2 Eye Content
1.3 The Cornea
1.4 The Sclera
1.5 The Uveal Tract
1.6 The Retina
1.7 The Aqueous Humor
1.8 The Lens
1.9 The Vitreous
References
2 Classification of Uveitis
2.1 Classification of Uveitis
2.2 Anatomic Classification
2.3 Classification Based on Course
2.4 Classification Based on Clinical and Pathological Features
2.5 Classification Based on Causative Agents
References
Part II Diagnosis of Uveitis
3 History-Taking in Uveitis Patients
3.1 Overview
3.2 Geographical and Racial Distribution of Uveitis
3.3 Age at Onset of Uveitis
3.4 Sex Distribution in Uveitis
3.5 Unilateral or Bilateral Involvement
3.6 Family History
3.7 Personal History
3.8 Systemic Manifestations (Systemic Disorders)
References
4 Ocular Examinations
4.1 The Purposes of Ocular Examinations in Uveitis Patients
4.2 Visual Acuity
4.3 Lid Changes May Be Associated with the Following Entities of Uveitis
4.4 Conjunctival Changes May Be Seen in the Following Uveitis Entities
4.5 Episcleritis
4.6 Scleritis
4.7 Red Reflex Through the Sclera
4.8 Corneal Changes
4.9 Ciliary Injection
4.10 Keratic Precipitates (KPs)
4.11 Anterior Chamber Alterations
4.12 Changes in the Iris and Pupil
4.13 Changes of the Anterior Chamber Angle
4.14 Changes of the Lens
4.15 Changes of the Vitreous
4.16 The Fundus Changes in Uveitis
References
5 Auxiliary Ocular Examinations
5.1 Ultrasound Biomicroscopy (UBM)
5.1.1 Overview
5.1.2 The Changes Disclosed by UBM in Uveitis Patients
5.2 Ultrasonography
5.2.1 Overview
5.2.2 The Changes Detected by Ultrasonography in Uveitis Patients
5.3 Fundus Fluorescein Angiography (FFA)
5.3.1 Overview
5.3.2 The Changes Detected by FFA in Uveitis Patients
5.4 Indocyanine Green Angiography (ICGA)
5.4.1 Overview
5.4.2 The Changes Detected by ICGA in Uveitis Patients
5.5 Optical Coherence Tomography (OCT) Imaging
5.5.1 Overview
5.5.2 The Changes Disclosed by OCT in Uveitis Patients
References
6 Systemic Imaging and Laboratory Investigations
6.1 X-ray
6.2 Computed Tomography (CT)
6.3 Magnetic Resonance Imaging (MRI)
6.4 Laboratory Investigations
References
Part III Treatment of Uveitis
7 Ideology, Fundamental Principles, and Strategies in Management of Uveitis
7.1 Ideology in Uveitis Management
7.2 Fundamental Principles
7.3 Strategies
References
8 Corticosteroids
8.1 Overview
8.2 Topical Corticosteroids
8.3 Periocular Corticosteroids
8.4 Intravitreal Corticosteroids
8.5 Systemic Corticosteroids
References
9 Steroid-sparing Immunosuppressive Agents
9.1 Overview
9.2 Cyclophosphamide
9.3 Chlorambucil
9.4 Cyclosporine A (CsA)
9.5 FK506
9.6 Methotrexate
9.7 Azathioprine
9.8 Mycophenolate Mofetil
9.9 Biological Agents
References
10 Non-steroidal Anti-inflammatory Drugs
10.1 Overview
10.2 Topical NSAIDs
10.3 Systemic NSAIDs
References
11 Complications and Their Management
11.1 Overview
11.2 Cataract
11.3 Ocular Hypertension and Glaucoma
11.4 Macular Edema
References
Part IV Specific Uveitis Entities, Scleritis and Episcleritis
12 Acute Anterior Uveitis
12.1 Definition
12.2 Epidemiology
12.3 Common Entities
12.4 Less Common Entities
12.5 Symptoms
12.6 Signs
12.7 Complications
12.8 Diagnosis
12.9 Differential Diagnosis
12.10 Treatment
12.11 Prognosis
References
13 Intermediate Uveitis
13.1 Definition
13.2 Epidemiology
13.3 Etiology and Pathogenesis
13.4 Clinical Manifestations
13.4.1 Symptoms
13.4.2 Signs
13.5 Complications
13.6 Diagnosis
13.7 Differential Diagnosis
13.8 Treatment
13.9 Prognosis
References
14 Posterior Uveitis
14.1 Definition
14.2 Epidemiology
14.3 Etiology and Pathogenesis
14.4 Entities of Posterior Uveitis
14.5 Diagnosis and Differential Diagnosis
14.6 Treatment
14.7 Prognosis
References
15 Uveitis Associated with Ankylosing Spondylitis
15.1 Definition
15.2 Epidemiology
15.3 Etiology and Pathogenesis
15.4 Systemic Manifestations
15.5 Ocular Manifestations
15.6 Complications
15.7 Diagnosis
15.8 Differential Diagnosis
15.9 Treatment
15.10 Prognosis
References
16 Uveitis Associated with Reactive Arthritis
16.1 Definition
16.2 Epidemiology
16.3 Systemic Manifestations
16.4 Ocular Manifestations
16.5 Diagnosis
16.6 Differential Diagnosis
16.7 Treatment
16.8 Prognosis
References
17 Uveitis Associated with Psoriasis
17.1 Definition
17.2 Epidemiology
17.3 Etiology and Pathogenesis
17.4 Systemic Manifestations
17.5 Ocular Manifestations
17.6 Complications
17.7 Diagnosis
17.8 Differential Diagnosis
17.9 Treatment
17.10 Prognosis
References
18 Uveitis Associated with Inflammatory Bowel Diseases
18.1 Definition
18.2 Epidemiology
18.3 Etiology and Pathogenesis
18.4 Systemic Manifestations
18.5 Ocular Manifestations
18.6 Complications
18.7 Diagnosis
18.8 Differential Diagnosis
18.9 Treatment
18.10 Prognosis
References
19 Anterior Uveitis Associated with Herpesviruses
19.1 Definition
19.2 Epidemiology
19.3 Etiology and Pathogenesis
19.4 Clinical Manifestations
19.5 Complications
19.6 Diagnosis
19.7 Differential Diagnosis
19.8 Treatment
19.9 Prognosis
References
20 Fuchs Syndrome
20.1 Definition
20.2 Epidemiology
20.3 Etiology and Pathogenesis
20.4 Clinical Manifestations
20.5 Complications
20.6 Diagnosis
20.7 Differential Diagnosis
20.8 Treatment
20.9 Prognosis
References
21 Posner-Schlossman Syndrome
21.1 Definition
21.2 Epidemiology
21.3 Etiology and Pathogenesis
21.4 Clinical Manifestations
21.5 Complications
21.6 Diagnosis
21.7 Differential Diagnosis
21.8 Treatment
21.9 Prognosis
References
22 Uveitis in Children
22.1 Definition
22.2 Epidemiology
22.3 Specific Concerns About Uveitis in Children
22.4 Complications
22.5 Diagnosis
22.6 Treatment
22.7 Prognosis
References
23 Uveitis-associated with Juvenile Idiopathic Arthritis
……
