
作者:AbulK.Abbas
页数:319
出版社:北京大学医学出版社
出版日期:2020
ISBN:9787565922916
电子书格式:pdf/epub/txt
内容简介
More specifically,we have focused on the following objectives.First,we have presented the most important principles governing the function of the immune sys-tem by synthesizing key concepts from the vast amount of experimental data that have emerged in the field of immunology.Our judgment of what is most important is based largely on what is most clearly established by scientific investigation and is essential for understand-ing the major functions of the immune system.We have also prioritized content that is relevant to human health and disease.We have realized that in any con- cise discussion of complex phenomena,it is inevitable that exceptions and caveats cannot be considered in detail,so these have largely been omitted.Second,we have focused on immune responses against infectious microbes,and most of our discussions of the immune system are in this context.Third,we have made liberal use of illustrations to highlight important principles,but we have reduced factual details that may be found in more comprehensive textbooks.Fourth,we have also discussed immunologic diseases from the perspec-tive of principles,emphasizing their relation to normal immune responses and avoiding details of clinical syn-dromes and treatments.We have included selected clin-ical cases in an appendix to illustrate how the principles ofimmunology may be applied to common human dis-eases.Finally,in order to make each chapter readable on its own,we have repeated key ideas in different places in the book.We feel such repetition will help students to grasp the most important concepts.
目录
2 Innate Immunity,The Early Defense Against Infections
3 Antigen Capture and Presentation to Lymphocytes,What Lymphocytes See
4 Antigen Recognition in the Adaptive Immune System,Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires
5 T Cell-Mediated Immunity,Activation of TLymphocytes
6 Effector Mechanisms of T Cell-Mediated Immunity,Functions of T CeHs in Host Defense
7 Humorallmmune Responses,Activation of B Lymphocytes and Production of Antibodies
8 Effector Mechanisms of Humorallmmunity,Elimination of Extracellular Microbes and Toxins
9 Immunologic Tolerance and Autoimmunity,Self-Nonself Discrimination in the Immune System and Its Failure
10 Immunology of Tumors and Transplantation,
Immune Responses to Cancer Cells and Normal Foreign Cells
11 Hypersensitivity,Disorders Caused by Immune Responses
12 Congenital and Acquired Immunodeficiencies,
Diseases Caused by Defective Immunity
Selected Readings,Glossary,
Appendix Ⅰ: Principal Features of Selected CD Molecules
Appendix Ⅱ: Cytokines,
Appendix Ⅲ: Clinical Casesr
Index,















